Saint Bernese - (Saint Bernard x Bernese Mountain Dog mix)
Saint Berdoodle - (Saint Bernard x Poodle mix)
Saint Bermastiff - (Mastiff x Saint Bernard mix)
Saint Bernewfie- (Saint Bernard x Newfoundland mix)
Saint Berxer - (Saint Bernard x Boxer mix)
Saint Dane - (Great Dane x Saint Bernard mix)
Saint Pyrenees - (Saint Bernard x Great Pyrenees mix)
Saint Shepherd - (Saint Bernard x German Shepherd mix)
Sammypoo - (Samoyed x Poodle mix)
Sceagle - (Beagle x Scottish Terrier mix)
Schapso - (Lhasa Apso x Miniature Schnauzer mix)
Schip-A-Pom - (Pomeranian x Schipperke mix)
Schipese - (Maltese x Schipperkemix)
Schipper-Poo - (Poodle x Schipperke mix)
Schnairedale - (Airedale Terrier x Schnauzer mix)
Schnau-Tzu - (Miniature Schnauzer x Shih Tzu mix)
Schnauffen - (Schnauzer x Affenpinscher mix)
Schneagle - (Beagle x Schnauzer mix)
Schnekingese - (Miniature Schnauzer x Pekingese mix)
Schnese - (Havanese x Miniature Schnauzer mix)
Schnocker - (Miniature Schnauzer x Cocker Spaniel mix)
Schnoodle - (Schnauzer x Poodle mix)
Schnorgi - (Schnauzer x Corgi mix)
Schnottie - (Schnauzer x Rottweiler mix)
Schnu - (Miniature Schnauzer x Shiba Inu mix)
Schnug - (Miniature Schnauzer x Pug mix)
Schweenie - (Dachshund x Shih Tzu mix)
Sco-Shi - (Scottish Terrier x Shih Tzu mix)
Scobo Terrier - (Boston Terrier x Scottish Terrier mix)
Scoland Terrier - (Scottish Terrier x Westie mix)
Scolden Terrier- (Scottish Terrier x Golden Retriever mix)
Scorkie - (Scottish Terrier x Yorkshire Terrier mix)
Scotchi - (Scottish Terrier x Chihuahua mix)
Scotchon - (Bichon Frise x Scottish Terrier mix)
Scotinese - (Pekingese x Scottish Terrier mix)
Scottese - (Maltese x Scottish Terrier mix)
Scotti Apso - (Lhasa Apso x Scottish Terrier mix)
Scottish Cocker - (Cocker Spaniel x Scottish Terrier mix)
Scottish-Skye Terrier - (Scottish Terrier x Skye Terrier mix)
Scottish Staffish Bull Terrier - (Scottish Terrier x Staffordshire Bull Terrier mix)
Scoodle - (Scottish Terrier x Poodle mix)
Sealydale Terrier - (Sealyham Terrier x Airedale Terrier mix)
Shairn-Inu - (Cairn Terrier x Shiba Inu mix)
Sharbo - (Boston Terrier x Chinese Shar-Pei mix)
Shar-Pei Pitbull Terrier - (Chinese Shar-Pei x American Pit Bull Terrier mix)  
Shar-Poo - (Shar-Pei x Poodle mix)
Shar Tzu - (Shar-Pei x Shih Tzu mix)
Sharberian Husky - (Chinese Shar-pei x Siberian Husky mix)
Sharmatian - (Chinese Shar-Pei x Dalmatian mix)
Sharp Eagle - (Beagle x Chinese Shar Pei mix)
Sheepadoodle - (Old English Sheepdog x Standard Poodle mix)
Shel-Aussie - (Australian Shepherd or Miniature Australian Shepherd x Shetland Sheepdog mix)
Shelchon - (Bichon Frise x Shetland Sheepdog mix)
Shelestie - (Shetland Sheepdog x West Highland White Terrier mix)
Shelillon - (Papillon x Shetland Sheepdog mix)
Sheltidoodle - (Sheltie x Poodle mix)
Sheltie Inu - (Shetland Sheepdog x Shiba Inu mix)
Sheltie-Kee - (Keeshond x Shetland Sheepdog mix)
Sheltie Pin- (Shetland Sheepdog x Miniature Pinscher mix)
Sheltie Pug- (Shetland Sheepdog x Pug mix)
Sheltie Shepherd - (German Shepherd x Shetland Sheepdog mix)
Sheltie Tzu- (Shetland Sheepdog x Shih Tzu mix)
Shepadoodle - (German Shepherd x Standard Poodle mix)
Shepherd Pit- (German Shepherd x American Pitbull Terrier mix)
Sheprador - (Australian Shepherd x Labrador Retriever mix)
Shepweiler - (German Shepherd x Rottweiler mix)
Shethund - (Shetland Sheepdog x Dachshund mix)
Shetinese - (Pekingese x Shetland Sheepdog mix)
Shi-Beagle - (Beagle x Shiba Inu mix)
Shiba-Chi - (Chihuahua x Shiba Inu mix)
Shiba Corgi - (Shiba Inu x Welsh Corgi mix mix)
Shiba Pin - (Shiba Inu x Miniature Pinscher mix)
Shibadox - (Shiba Inu x Dachshund mix)
Shibos - (Boston Terrier x Shiba Inu mix)
ShiChi - (Chihuahua x Shih Tzu mix)
Shichon - (Bichon Frise x Shih Tzu mix)
Shiffon - (Brussels Griffon x Shih Tzu mix)
Shih Apso - (Lhasa Apso x Shih Tzu mix)
Shih-Mo - (American Eskimo x Shih Tzu mix)
Shih-Poo - (Shih-Tzu x Poodle mix)
Shinese - (Shih Tzu x Pekingese mix)
Shiranian - (Pomeranian x Shih Tzu mix)
Shocker - (Cocker Spaniel x Shiba Inu mix)
Shockerd - (English Shepherd x Cocker Spaniel mix)
Shollie- (German Shepherd x Collie mix)
Shorgi - (Corgi x Shih-Tzu mix)
Shorkie Tzu - (Shih Tzu x Yorkie mix)
Shug - (German Shepherd Dog x Pug mix)
Sibercaan - (Siberian Husky or Native American Indian Dog x Canaan Dog mix)
Siberian Boston - (Siberian Husky x Boston Terrier mix)
Siberian Cocker - (Cocker Spaniel x Siberian Husky mix)
Siberian Indian Dog - (Siberian Husky x Native American Indian Dog mix)
Siberian Pinscher - (Doberman Pinscher x Siberian Husky mix)
Siberian Retriever- (Siberian Husky x Labrador Retriever mix)
Siberian Shiba- (Siberian Husky x Shiba Inu mix)
Siberpoo - (Siberian Husky x Poodle mix)
Silkchon - (Bichon Frise x Silky Terrier mix)
Silkese - (Maltese x Silky Terrier mix)
Silkin - (Japanese Chin x Silky Terrier mix)
Silkinese - (Pekingese x Silky Terriermix)
Silkland Terrier - (Silky Terrier x Westie mix)
Silkshire Terrier - (Silky Terrier x Yorkshire Terrier mix)
Silkshund - (Dachshund x Silky Terrier mix)
Silky Cairn - (Cairn Terrier x Silky Terrier mix)
Silky Cocker - (Maltese x Cocker Spaniel mix)
Silky Coton - (Coton de Tulear x Silky Terrier mix)
Silky Jack - (Jack Russell Terrier x Silky Terrier mix)
Silky-Lhasa - (Lhasa Apso x Silky Terrier mix)
Silky-Pin - (Miniature Pinscher x Silky Terrier mix)
Silky Pug - (Pug x Silky Terrier mix)
Silky Tzu - (Silky Terrier x Shih-Tzu mix)
Silkyhuahua - (Chihuahua x Silky Terrier mix)
Silkytie - (Shetland Sheepdog x Silky Terrier mix)
Silkzer - (Miniature Schnauzer x Silky Terrier mix)
Ski-Border - (American Eskimo x Border Collie mix)
Ski-Collie - (American Eskimo x Collie mix)
Skilky Terrier- (Scottish Terrier x Silky Terrier mix)
Skip-Shzu - (Schipperke x Shih Tzu mix)
Skye-Pap - (Skye Terrier x Papillon mix)
Skypoo - (Poodle x Skye Terrier mix)
Smooth Chisoxy - (Smooth Fox Terrier x Chihuahua mix)
Smooth Fo-Chon - (Bichon Frise x Smooth Fox Terrier mix)
Smooth Fo-Tzu - (Shih Tzu x Smooth Fox Terrier mix)
Smooth Foodle - (Poodle x Smooth Fox Terrier mix)
Smooth Fox Beagle - (Smooth Fox Terrier x Beagle mix)
Smooth Fox Pinscher - (Miniature Pinscher x Smooth Fox Terrier mix)
Smooth Foxie Doxie - (Smooth Fox Terrier x Dachshund mix)
Smooth Foxingese - (Pekingese x Smooth Fox Terrier mix)
Smooth Foxker - (Cocker Spaniel x Smooth Fox Terrier mix)
Smooth Foxillon - (Papillon x Smooth Fox Terrier mix)
Smooth Foxton - (Boston Terrier x Smooth Fox Terrier mix)
Smooth Foxy Rat Terrier - (American Rat Terrier x Smooth Fox Terrier mix)
Smooth Foxy Russell - (Jack Russell Terrier x Smooth Fox Terrier mix)
Smooth Jafox - (Japanese Chin x Smooth Fox Terrier mix)
Smooth Toy Foxter - (Toy Fox Terrier x Smooth Fox Terrier mix)
Smooth Pom Terrier - (Pomeranian x Smooth Fox Terrier mix)
Smooth Poxer - (Pug x Smooth Fox Terrier mix)
Smooth Scottish Fox Terrier - (Scottish Terrier x Smooth Fox Terrier mix)
Smooth Torkie - (Smooth Fox Terrier x Yorkie mix)
Sniffon - (Miniature Schnauzer x Brussels Griffon mix)
Snorkie - Miniature Schnauzer x Yorkshire Terrier mix)
Soft Coated Golden - (Golden Retriever x Soft Coated Wheaten mix)
Soft Coated Wheatzer - (Miniature Schnauzer x Soft Coated Wheaten Terrier mix)
Soft Coated Woxer - (Boxer x Soft Coated Wheaten mix)
Spanador - (Labrador Retriever x American Spaniel mix)
Spangold Retriever - (English Springer Spaniel x Golden Retriever mix)
Spanierd - (English Springer Spaniel x German Shepherd Dog mix)
Spantriever - (English Cocker Spaniel x Labrador Retriever mix)
Spreagle - (English Springer Spaniel x Beagle mix)
Springer Pit- (English Springer Spaniel x American Pit Bull Terrier mix)
Springer Rottie - (English Springer Spaniel x Rottweiler mix)
Springer Spaniel Sheepdog - (English Springer Spaniel x Old English Sheepdog mix)  
Springerdoodle - (English Springer Spaniel x Poodle mix)
Sprocker Spaniel- (English Springer Spaniel x Cocker Spaniel mix)
Sprollie - (English Springer Spaniel x Collie mix)
Staffy Bull Bullmastiff - (Staffordshire Bull Terrier x Bullmastiff mix)
Staffweiler - (American Staffordshire Terrier x Rottweiler mix)
St. Weiler - (Rottweiler x St. Bernard mix)
Staffie Bullweiler - (Staffordshire Bull Terrier x Rottweiler mix)
Staffy Bull Pit - (Staffordshire Bull Terrier x Pit Bull Terrier mix)
Standard Auss-Tzu- (Australian Shepherd x Shih Tzu mix)
Standard Bolonauzer - (Bolognese x Standard Schnauzer mix)
Standard Border Schnollie - (Border Collie x Standard Schnauzer mix)
Standard Irish Wolf Schnauzer - (Standard Schnauzer x Irish Wolfhound mix)
Standard Kerry Blue Schnauzer - (Kerry Blue Terrier x Standard Schnauzer mix)
Standard Ratzer  - (Standard Schnauzer x Rat Terrier mix)
Standard Schnauzer Chin - (Japanese Chin x Standard Schnauzer mix)
Standard Schnoodle - (Poodle x Standard Schnauzer mix)
Standard Wauzer - (Westie x Standard Schnauzer mix)
Standard Wire Hair Snauzer - (Standard Schnauzer x Wire Fox Terrier mix)
Stump Double Cattle Dog - (Australian Stumpy Tail Cattle Dog x Australian Cattle Dog mix)
Swiss Bernese Mt. Dog - (Bernese Mountain Dog x Greater Swiss Mountain Dog mix)
Swiss Newfie - (Greater Swiss Mountain Dog x Newfoundland mix)
Swissy Saint - (Greater Swiss Mountain Dog x Saint Bernard mix)
Swissneese - (Great Swiss Mountain Dog x Great Pyrenees mix)